Luteinizing Hormone Levels Menopause
On the change of luteinizing hormone level during menopause
When a woman goes through menopause, there are significant changes in all kinds of physiology of the body. Among them, the fluctuation of luteinizing hormone (Luteinizing Hormone) level is particularly critical.
Before menopause, a woman's ovary function is healthy, and the hypothalamus-pituitary-ovary axis is coordinated and orderly. The hypothalamus secretes gonadotropin-releasing hormone, which stimulates the anterior pituitary to secrete luteinizing hormone and follicle-stimulating hormone. The two cooperate to promote the development, maturation and ovulation of follicles in the ovary. At this time, the level of luteinizing hormone fluctuates regularly with the menstrual cycle.
Then to the menopausal stage, the ovarian function gradually declines. The number of follicles decreases sharply and the responsiveness to gonadotropin decreases The feedback regulation of the hypothalamus-pituitary-ovarian axis is unbalanced, and the pituitary senses the decrease in the secretion of ovarian hormones, so it increases the secretion of luteinizing hormone. Therefore, during menopause, the level of luteinizing hormone often increases significantly.
This increase is not only a change in numbers, but also related to many physiologies of the body. Although high levels of luteinizing hormone are a compensatory response of the body trying to maintain ovarian function, the ovaries are no longer able to cope with it. It may cause hot flashes, night sweats, and upset menopausal symptoms. Elevated luteinizing hormone can affect the function of the autonomic nervous system and disrupt the body temperature regulation center.
And abnormal levels of luteinizing hormone are also associated with postmenopausal diseases such as cardiovascular disease and osteoporosis. Because estrogen levels decrease with the decline of ovarian function, the protective ability of cardiovascular and bone is gradually lost, and luteinizing hormone is increased, which may further exacerbate this pathological process.
In summary, understanding the changes in luteinizing hormone levels during menopause is of great significance for understanding menopausal physiology and preventing and treating menopausal-related diseases. Doctors can use this as a basis to customize precision prevention and treatment strategies for menopausal women to improve their quality of life and protect their health.
